15,000
Square feet of lab space
500+
GPU cores for computation
24/7
Facility access for researchers
$10M
Equipment value
Spectroscopy
Many of our primary research questions foucs on the association between the abnormal metabolism and disaese phenotype. This requires accurate measurement of several biomakers through approaches such as liquid chromatography tandem mass spectrometry (LC-MS/MS). Our spectroscopy equipment is the heart and soul of our laboratory. This work has led to the identificaition and clinical validation of novel biomakers, and demonstration that new therapeutic approaches and improve the abnormal biochemistry in various model systems.
- Waters H-Class UPLC system
- Waters TQD Triple Quadrupole MS
- Waters Tunable UV (TUV) detector
- Waters Fluorescence (FLR) detector
Disease Model Systems
Our reserach has primarly foucsed on two rare diseases: pyridoxine-dependent epilepsy (PDE-ALDH7A1) and glutaric aciduria type 1 (GA1). To study PDE-ALDH7A1 we utize both e.coli and yeast systems to evalute the impact of disease variants and animal models to answer complex questions about diease mechanism. Although Dr. Woontner played a significant role in the develoment of the GA1 murine model, we have moved to a zebrafish model of GA1.
- Samples from study participants
- E.coli based expression system for ALDH7A1
- Mouse model of PDE-ALDH7A1
- Zebrafish models of PDE-ALDH7A1 and GA1
Patient Engagement
Our reserach has primarly foucsed on two rare diseases: pyridoxine-dependent epilepsy (PDE-ALDH7A1) and glutaric aciduria type 1 (GA1). To study PDE-ALDH7A1 we utize both e.coli and yeast systems to evalute the impact of disease variants and animal models to answer complex questions about diease mechanism. Although Dr. Woontner played a significant role in the develoment of the GA1 murine model, we have moved to a zebrafish model of GA1.
- Samples from study participants
- E.coli based expression system for ALDH7A1
- Mouse model of PDE-ALDH7A1
- Zebrafish models of PDE-ALDH7A1 and GA1
Core Research Equipment
Our comprehensive instrumentation supports diverse research needs across multiple disciplines
High-Performance Computing Cluster
500+ GPU cores, 100TB storage, redundant systems for maximum uptime and computational power.
Electron Microscopy Suite
Scanning and transmission electron microscopes for nanoscale materials characterization.
Spectroscopy Laboratory
Complete range of analytical instruments including NMR, FTIR, and mass spectrometry.
Clean Room Facilities
Class 100 and 1000 clean rooms for sensitive sample preparation and device fabrication.
Biological Safety Labs
BSL-2 certified laboratories with specialized ventilation and containment systems.
3D Printing & Fabrication
Rapid prototyping capabilities for custom research equipment and sample holders.
Safety First Philosophy
Safety is fundamental to our research mission. All facilities operate under strict safety protocols with regular training, equipment maintenance, and compliance audits.
Key Safety Features:
- Emergency Response: 24/7 emergency response team and automated safety systems
- Training Programs: Mandatory safety training for all researchers and regular refresher courses
- Equipment Maintenance: Preventive maintenance schedules and real-time monitoring systems
- Regulatory Compliance: Full compliance with OSHA, EPA, and institutional safety requirements
Environmental Responsibility:
- Energy-efficient equipment and LED lighting throughout facilities
- Waste minimization programs and proper hazardous waste disposal
- HVAC systems optimized for both safety and energy conservation
- Sustainable procurement policies for equipment and supplies
Plan Your Visit
Experience Our Facilities Firsthand
Visit Us
Research Lab
Science Building, University of Excellence
123 Science Drive
Excellence City, EC 12345
Office Hours
Monday - Friday: 8:00 AM - 6:00 PM
Saturday: 9:00 AM - 2:00 PM
Sunday: By appointment only