Kristie Pauly

Kristie Pauly joined the Coughlin laboratory in 2018 to lead the work focused on from Harvard Medical School. Alex’s research focuses on systems biology approaches to understanding disease mechanisms and identifying therapeutic targets.

Research Interests

Alex specializes in:

• Building computational models of cellular signaling networks
• Integrating multi-omics data to understand disease states
• Identifying drug repurposing opportunities through network analysis
• Developing tools for systems-level analysis of biological data

Key Publications

• Wong A, et al. (2023). “Network-based drug repurposing for COVID-19.” Science Translational Medicine.
• Wong A, et al. (2022). “Multi-omics integration reveals disease mechanisms.” Nature Biotechnology.
• Wong A, et al. (2021). “Systems biology of cancer drug resistance.” Cell Systems.