Curtis Coughlin II
About the Lab
Dr. Curtis Coughlin leads the research laboratory at the University of Colorado Anschutz. He completed his doctoral training with Dr. Stephen Goodman’s, whose reserach lab focused on glutraic aciduria type 1 for 45 years. The Coughlin laboratory primary focus is lysine metabolism, which led to the identification of a novel metabolite within the degradation of lysine. This metabolites was later applied to newborn screening for PDE-ALDH7A1. Dr. Coughlin also prioritizes collabortive research approaches. Along with Dr. Clara van Karnebeek and members of the International PDE Consortium, he helped establish the use of lysine reduction therapies for the treatment of PDE-ALDH7A1.
Beautiful data visualization workspace
Research Vision
Our lab focuses on developing and applying cutting-edge machine learning techniques to solve complex biological problems. We work at the intersection of computer science, biology, and medicine to:
- Predict protein structures and functions using deep learning models
- Discover new drug targets through computational screening
- Analyze genomic data to understand disease mechanisms
- Develop open-source tools for the scientific community
Leadership & Mentorship
Dr. Coughlin has mentored several learners including indivduials in master degree and PhD progams, medical students and residents, and junior faculty members. He has completed several formal mentoring programs and is committed to fostering an inclusive and collaborative research environment where all team members can thrive.
Awards & Recognition
- 2023 - National Science Foundation CAREER Award
- 2022 - Chan Zuckerberg Initiative Investigator
- 2021 - MIT Technology Review Innovator Under 40
- 2020 - NIH New Innovator Award
Join Our Team
We are always looking for passionate researchers to join our lab. If you’re interested in working at the forefront of computational biology and machine learning, please contact us with your CV and research interests.
