Curtis Coughlin II

About the Lab

Dr. Curtis Coughlin leads the research laboratory at the University of Colorado Anschutz. He completed his doctoral training with Dr. Stephen Goodman, and fondly remembers coffee fueled discussions about GA1 with Drs. Goodman and Woontner. He has been fortunate to have several excellent mentors throughout his career. He prioritizes team-science and has worked with many amazing colleagues such as Professor Sidney Gospe Jr and Clara van Karnebeek who continue to teach him about pyridoxine-dependent epilepsy.

Leadership & Mentorship

Dr. Coughlin has mentored several learners including individuals in master degree and PhD programs, medical students and residents, and junior faculty members. He has completed several formal mentoring programs and is committed to fostering an inclusive and collaborative research environment where all team members can thrive.

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Self-Reported Health-Related Quality of Life (HRQoL) in Adults With Urea Cycle Disorders featured image

Self-Reported Health-Related Quality of Life (HRQoL) in Adults With Urea Cycle Disorders

This paper evaluated self-reported health-quality of life in adults with a urea cycle disorders

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Curtis Coughlin II
Kristie wins the Shapira Award! featured image

Kristie wins the Shapira Award!

Kristie is named the recipient of the 2025 Emmanual Shapira award for her work on newborn screening for PDE-ALDH7A1

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Curtis Coughlin II
GA1: How natural history studies support the development of new treatments featured image

GA1: How natural history studies support the development of new treatments

GA1 webinar led by the Coughlin Lab

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Curtis Coughlin II
Epilepsy disease classification: a community effort to enhance the Mondo Disease Ontology featured image

Epilepsy disease classification: a community effort to enhance the Mondo Disease Ontology

This paper alighted epilepsy heiarchy in MONDO with the International Leaague Against Epilepsy (ILAE) classification system

Nicole Vasilevsky
PDE-ALDH7A1 consensus guidelines and current advances in treatment featured image

PDE-ALDH7A1 consensus guidelines and current advances in treatment

PDE-ALDH7A1 confernece at Oslo Univeristy Hospital

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Curtis Coughlin II
The History and Nosology of the Glycine Disorders: A Framework for Clinicians featured image

The History and Nosology of the Glycine Disorders: A Framework for Clinicians

Characteristic clinical and biochemical features of each condition, as well as non-genetic phenocopies that cause hyperglycinaemia.

Arthavan Selvanathan
Winter Holiday Party 2025 featured image

Winter Holiday Party 2025

Science is fun. Science is curiosity. We all have natural curiosity...

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Curtis Coughlin II
It’s All About the Vitamins [B]aby! featured image

It’s All About the Vitamins [B]aby!

This ACMG webinar focuses on treatable metabolic disorders

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Curtis Coughlin II
When everyday counts: Neonatal treatment for pyridoxine-dependent epilepsy. featured image

When everyday counts: Neonatal treatment for pyridoxine-dependent epilepsy.

Dr. Coughlin discusses current treatment of PDE-ALDH7A1

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Curtis Coughlin II
HMGGP Annual Retreat featured image

HMGGP Annual Retreat

Nicole presents her recent work from the Coughlin Lab

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Curtis Coughlin II